Quality control materials play a critical role in ensuring the accuracy, reliability, and consistency of newborn screening (NBS) assays. These materials are used by laboratories to monitor assay performance, verify instrument functionality, and maintain compliance with quality assurance requirements throughout routine testing.

Bome Trivitron develops specialized quality control materials designed for newborn screening applications across immunoassay, molecular, and chromatographic platforms. Produced to closely mimic the characteristics of dried blood spot (DBS) samples used in screening programs, Bome Trivitron’s control products support assay validation, routine quality monitoring, and inter-laboratory standardization. By providing stable and well-characterized controls, Bome Trivitron helps laboratories maintain high testing standards and ensure reliable results for national newborn screening programs.

Chromatographic technologies are fundamental to modern newborn screening, enabling the precise separation and quantification of metabolic biomarkers associated with inherited disorders. Techniques such as high-performance liquid chromatography (HPLC), gas chromatography–mass spectrometry (GC-MS), and liquid chromatography–tandem mass spectrometry (LC-MS/MS) provide high analytical sensitivity, specificity, and the ability to detect multiple metabolites in a single analysis.

Bome Trivitron develops chromatographic kits and reagents specifically designed for newborn screening laboratories. Optimized for the analysis of dried blood spot (DBS) samples, these solutions support the detection of key biomarkers related to amino acid disorders, organic acidemias, and fatty acid oxidation defects. By combining validated reagents with robust chromatographic workflows and compatibility with modern analytical instruments, BT’s solutions enable accurate, reliable, and scalable newborn screening programs.